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Learn Why We Age &
How To Slow Down the Onset of
Age Related Ailments
Cell
is the fundamental component
of all living organisms
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How
Cellular Damage
Relates to Aging |
 | FREE RADICALS
Damage
Free radicals are molecular
miscreants, compound substances that create havoc inside cells by
stripping other molecules of their electrons. Was there a direct link
between free radicals and aging? Was it possible that free radicals actually
contributed to aging?...Ames
estimates that the DNA in each cell of the human body experiences at least
100,000 "hits," or instances, of free radical damage per day.
(Learn more about free radicals. |
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 | MITOCHONDRIA
Damage Mitochondria
is the
"weak link in aging." Evidence has been piling up, that
deterioration of mitochondria is
an important cause of aging.
A significant cause of this
deterioration is the accumulation of destructive free
radicals - byproducts of normal metabolism - that
disable enzymes and other
chemicals. |
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 | OXIDATION
Damage In aging,
you're oxidizing the
proteins in mitochondria and they lose activity.
"If some of that lost activity is due to binding for substrate or coenzyme. |
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 | INFLAMMATION
Damage Chronic inflammation has been identified as a
risk factor for numerous age-related diseases and shorter, less healthy
lives. In effect, inflammation
acts as a source of damage to the complex biological machines that are our
bodies.
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Learn
How To Maintain Cellular Health
and Rejuvenate Cellular Damage
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Anti-Oxidation
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Anti-Inflammatory
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Cellular Health |
Cell
Rejuvenation |
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Acid/Alkaline
Balance |
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Enzyme:
A substance (usually a protein) that speeds up, or catalyzes,
a chemical reaction without being permanently altered or consumed.
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Proteins:
Proteins are
intensely studied by biomedical researchers because these molecules are
involved in nearly every biological function. Proteins include the enzymes
that allow the chemical reactions necessary to life to take place
efficiently. They also include many of the hormones that regulate growth
and development. They are important components of the cell's physical
structure, making up half of the cell's dry weight. They help transmit
messages from nerve cells and work in muscle cells to convert chemical
energy into mechanical energy, which permits movement. Proteins in the
cell membrane control molecules entering and leaving the cell. Hemoglobin
proteins in red blood cells transport oxygen through the bloodstream, and
antibody proteins fight infection. Proteins are made of strings of amino
acids ordered according to instructions contained in the DNA. A protein's
primary structure is this linear chain of amino acids; however, almost
immediately after it is created the chain springs into helices, sheets, or
other shapes that form the protein's secondary structure. The shapes then
fold and coil further into a complex, three-dimensional structure. This is
the active form of the protein that can bind to, and interact with, other
molecules.
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Lysosomes:
When a white blood cell engulfs a bacterium and destroys it, the white
blood cell's lysosomes do most of the work. They fuse with the vesicle of
engulfed material and release digestive enzymes to break up the material.
Similarly, when a cell takes in large molecules of food, enzymes in the
lysosomes break the food down into smaller and simpler products that the
cell can use.
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Peroxisome
appears to both generate and break down hydrogen peroxide, a corrosive
molecule composed of two atoms each of hydrogen and oxygen.
Peroxisomal enzymes remove hydrogen atoms from these small
molecules and join the hydrogen to atoms of oxygen to form hydrogen
peroxide. One of the peroxisomal enzymes, catalase, then neutralizes the
hydrogen peroxide by catalyzing its breakdown into water and oxygen.
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Mitochondria:
The cell organelle that converts the energy in sugars into ATP (compound
that serves as a source of energy for the physiological reactions in
cells.), thereby fueling the cell. It is a convenient way for cells
to store the energy they need for such processes as protein manufacture,
DNA replication, and the construction of new organelles. Scientists
have long suspected that defects in mitochondrial genes could lead to
inherited disease in the same way that mistakes in nuclear DNA do.
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Figure 1: Cellular Structure
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